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Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate 98%min


Appearance: White to off white solid
Melting point: 60-63 °C (lit.)
Boiling point: 132°C/0.4mmHg(lit.)
Predicted Density: 1.37± 0.1g /cm3
Solubility: Chloroform, Ethyl Acetate
Predicted Acidity coefficient (pKa): -2.19±0.29(Predicted)
Morphology: Solid

Safety information

Danger symbol (GHS):

Warning word: Warning
Hazard description: H315-H319-H335
Precautions: P261-P264-P271-P280-P302+P352-P305+P351+P338
Danger Class code: 36/37/38
Safety Instructions:26-36
WGK Germany: 3
Hazard Note :Irritant
HS Code: 29339900

products detail

Storage Condition
Store in a cool, dry, well-ventilated place, away from fire and heat sources.

Mode of transport
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate can be transported by road, rail, water and air. International and local transport regulations, laws and regulations should be observed during transportation.

Transport Condition
During transportation, high temperature, sun exposure, humidity and mechanical collision should be avoided to avoid affecting product quality.
The specific requirements for transporting Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate
may vary from country to country and region. It is recommended to consult relevant transport professionals and follow relevant regulations before transporting.

Packed in 25kg /50kg plastic drum, or packed according to customer needs.

Application Fields

Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate is an organic synthesis intermediate and pharmaceutical intermediate, mainly used in the synthesis of avanafil important intermediate. Avanafil is an oral, fast-acting, highly selective phosphodiesterase-5 (PDE-5) inhibitor used to treat erectile dysfunction in men.
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate as organic synthesis intermediates and pharmaceutical intermediates, used in laboratory research and development process and chemical pharmaceutical synthesis process.

Down-stream product

4-(ethylaMino)-2-(Methylthio)pyriMidine-5-carbaldehyde,(4-Chloro-2-methylsulfanyl-pyrimidin-5-yl)methanol ,4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde

Quality Specification

Characteristics White to off white solid
Water Content ≤0.5%
Purity(by HPLC) ≥98.0%
Assay(by HPLC) ≥98.0%

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